It is possible that obesity plays a factor in cancer recurrence in men who have has prostate cancer surgery. A new study out of Duke University Medical Center found that men who were both obese and diagnosed and treated for prostate cancer were three times more likely to see the cancer spread beyond the prostate than those of their thinner counterparts.
Prostate cancer is most common among older men. It forms in tissues of the prostate gland in the male reproductive system that is located below the bladder and in front of the rectum. The National Cancer Institute estimates indicate that 217,730 new cases of prostate cancer were diagnosed in 2010 among Americans alone, with 32,050 men losing their lives to the disease.
Recent years have seen an increase in both obesity and prostate cancer. Researchers conducted a study to see if there was a correlation. The evaluation followed 287 patients, who had undergone prostate removal surgery and androgen deprivation therapy (ADT). After five years post-op, patients who were obese were three times more likely to have seen the returning cancer spread beyond the prostate.
Dr Christopher Keto, lead author of the study, presented to the American Urological Association's annual conference on Sunday, said: "Over the past decades, there has been increasing prevalence of obesity in the U.S. and Europe, and a high rate of prostate cancer that is the second-most lethal cancer for men."
There is the possibility that the chemical level of androgen deprivation therapy may need to be adjusted for men who are obese. Currently the dosage remains the same, no matter the patient’s weight. He added that more studies will be needed to determine why obese men were more likely to see their cancers progress, even when treatment was the same across the board.
Prostate cancer is most common among older men. It forms in tissues of the prostate gland in the male reproductive system that is located below the bladder and in front of the rectum. The National Cancer Institute estimates indicate that 217,730 new cases of prostate cancer were diagnosed in 2010 among Americans alone, with 32,050 men losing their lives to the disease.
Recent years have seen an increase in both obesity and prostate cancer. Researchers conducted a study to see if there was a correlation. The evaluation followed 287 patients, who had undergone prostate removal surgery and androgen deprivation therapy (ADT). After five years post-op, patients who were obese were three times more likely to have seen the returning cancer spread beyond the prostate.
Dr Christopher Keto, lead author of the study, presented to the American Urological Association's annual conference on Sunday, said: "Over the past decades, there has been increasing prevalence of obesity in the U.S. and Europe, and a high rate of prostate cancer that is the second-most lethal cancer for men."
There is the possibility that the chemical level of androgen deprivation therapy may need to be adjusted for men who are obese. Currently the dosage remains the same, no matter the patient’s weight. He added that more studies will be needed to determine why obese men were more likely to see their cancers progress, even when treatment was the same across the board.
source: healthnews.com
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